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Excessive appetite doesn't always stem from a lack of willpower, as it's influenced by hormones, metabolism, diet composition, and daily habits

GLP-1 receptors are present in Sertoli and Leydig cells, which means that these drugs have the potential to directly affect testicular function in addition to improving hormonal balance

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Oral semaglutide (Rybelsus), approved in 2019, offers a non-injectable alternative (Kommu S et al., 2025)

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