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Ozempic as an add-on to basal insulin and Ozempic 1 mg vs 2 mg Primary endpoint: change in A1C from baseline SUSTAIN 5: add-on basal insulin 1,10,11 In adult patients with type 2 diabetes on basal insulin metformin Mean change in A1C from baseline at Week 30 Mean baseline A1C: SUSTAIN FORTE: Ozempic 1 mg vs 2 mg 1,8 In patients with type 2 diabetes on metformin sulfonylurea Mean change in A1C from baseline at Week 40 Mean baseline A1C: Results for SUSTAIN 5 and SUSTAIN FORTE based on sensitivity analyses of retrieved dropout population

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Product Specifications CAS Number: 910463-68-2 Synonym: NN9535 Peptide Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc--Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH Molecular Formula: CHNO Molecular Weight: 6 g/mol Purity: 95% (verified by HPLC and mass spectrometry) Packaging Format: 10 mg lyophilized powder in a sealed research-grade vial Storage Conditions: Store 28 C (20 C long term)

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