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Commonly reported side effects included: Nausea (the most frequently reported, particularly at higher doses) Vomiting Diarrhoea Decreased appetite Constipation Eructation (belching) At the 12 mg dose, gastrointestinal adverse events were reported in a higher proportion of participants compared with lower doses, though most did not lead to treatment discontinuation

Risks and benefits differ from FDA-approved GLP-1/GIP medications

In OASIS 4, Wegovy tablets 25mg led to average weight loss of 13.6% over 64 weeks, rising to 16.6% in people who stayed on treatment

Figure 4K)

The samples were diluted with 150 l of binding buffer