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Additionally, early research indicates it has antioxidant qualities

The compound incorporates three non-standard structural features: an -aminoisobutyric acid (Aib) at the N-terminus bearing no stereocenter, a D-2-naphthylalanine (D-2-Nal) at position 3, and a D-phenylalanine at position 4

doi: 10.1186/s13195-020-00754-8 134 ZhangZ.LiuJ.ZhengW.HouQ.ZhangL

Limitations include: Enzymatic and chemical degradation Poor membrane permeability Comparatively large molecular size When a peptide like epithalon is unmodified, bioavailability may be less than 1%

Proteome-wide profiling revealed that -halothioamide probes do not increase cellular promiscuity as compared to their -haloacetamide analogues, revealing their application as covalent tools for TCI development