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In the few individuals who did have preexisting cross-reactive antibodies, these often targeted the S2 region of spike that is more conserved across coronaviruses but that predominantly induces nonneutralizing antibodies [72, 73]

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More Stable B12 Levels: For some, a consistent daily oral dose might help smooth out any peaks and troughs in B12 levels that could occur between injections, leading to more consistent energy and symptom control

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