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It activates AMPK, the same metabolic switch your body flips during exercise

Oral might help gut issues but evidence is limited

Contraindications include known hypersensitivity to any component of the injection (including cobalt hypersensitivity), a history of severe reactions to thiamine/pyridoxine/cobalamin injections, and Lebers hereditary optic neuropathy (for B12-containing products)

Others pair semaglutide with protocols focused on anti-aging or athletic performance