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Between-group comparisons used independent samples t -tests, while intra-group longitudinal changes were analyzed with paired t -tests

These side effects generally dissipate within the first few weeks of treatment

Thyroid hormones act indirectly to increase sex hormone-binding globulin production by liver via hepatocyte nuclear factor-4

Regular physical activity, especially during fasting periods or before meals, increases fatty acid mobilization and creates the conditions where enhanced carnitine-mediated transport could theoretically make a difference

Employers that approach GLP-1 coverage thoughtfullythrough structured eligibility criteria, integrated health programs, and clear governanceare better positioned to manage costs while supporting employee health outcomes in an evolving benefits landscape.