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The oxygen-carrying function of the RBC results in the generation of oxygen radicals from cellular metabolism, leading to constant exposure to endogenous and exogenous sources of oxidative stress

In some embodiments, the percentage of active pharmaceutical ingredient is varied between about 0.01% and about 20%, between about 0.01% and about 10%, between about 0.01% and about 5% or more of the weight or volume of the total pharmaceutical formulation or composition

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