Muscogiuri G, Barrea L, Di Somma C, Altieri B, Vecchiarini M, Orio F, et al
Breastfeeding For women considering GLP-1 medications while breastfeeding, our guide on taking GLP-1 while breastfeeding covers the current safety data and recommendations for both medications
Food and Drug Administration (FDA) approved 2.4-mg doses of semaglutide as a way reduce the risk of major adverse cardiovascular events in patients who are overweight or obese and present with cardiovascular disease (CVD)
This interaction requires monitoring of thyroid parameters when initiating or adjusting either medication
In the direct comparison of tirzepatide versus semaglutide, we observed CIs compatible with no difference and point estimates indicating a modest numeric advantage of semaglutide, if any, for reducing MACE, particularly among patients at high cardiovascular risk