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[50] However, it is important to note that fenfluramine, rimonabant and lorcaserin used very different molecular mechanisms (acting mainly on serotonin 2c receptors [51] in the hypothalamus [52] or CB1 receptors [53] ) from GLP1R, GIPR or GR agonists and likewise do not imply anything on the possible dangers of GLP1R, GIPR or GR agonists

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The American College of Gastroenterology's 2017 guideline on drug-induced liver injury provides a grading framework for hepatotoxicity that can guide decision-making if transaminases rise

10.1002/bab.1584 3 AhrnB.SimonssonE.LarssonH.Landin-OlssonM.TorgeirssonH.JanssonP

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