Sural nerve pathology in diabetic patients with minimal but progressive neuropathy
Cardioprotective attributes
Symptomatic oHCM is a genetic condition where patients have thickened heart muscles and reduced blood flow from the left side of the heart to the rest of the body causing shortness of breath, fatigue, and potentially life-threatening events
4, the vast majority of the GLP-1 stimulatory activity was present in the greater than 100 kDa fraction of the bacterial supernatants (2507 1000 pM of GLP-1 for JA1, 1998 570 pM of GLP-1 for ATCC 12228 compared to 482 20 pM for the media control) with little activity remaining in the less than 100 kDa fractions (752 625 pM of GLP-1 for JA1, 545.3 363.5 pM of GLP-1 for ATCC 12228, compared to 487 182 pM for the media control) and no activity in the less than 3 kDa fraction (410 131 pM of GLP-1 for JA1, 347 85 pM of GLP-1 for ATCC 12228 compared to 482 20 pM for the media control)
21 Remarkably, even in HF-free patients with morbid obesity, cardiac abnormalities can be seen that are consistent with left ventricular (LV) remodelling and dysfunction, including greater LV mass, LV diastolic dysfunction and elevated LV filling pressure