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67 Non-proliferative astrogliosis typically occurs in neural tissue that is responding to a pathology but is not overtly damaged and retains its basic tissue architecture, for example (i) during diffuse neuroinflammation caused by peripheral exposure to microbial antigens such as lipopolysaccharide (LPS), 68,69 (ii) in tissue regions that are at a distance from focal lesions (diaschisis) caused by stroke, trauma or autoimmune attack, 8,70 or (iii) in tissue undergoing neurodegenerative changes

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Different to baseline, at 4 months NADPH associated with several metabolite of purine metabolism, such as hypoxanthine, inosine monophosphate (IMP), cyclic adenosine monophosphate (cAMP) and allantoin (Fig

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Escherichia coli PQQ-containing quinoprotein glucose dehydrogenase: Its structure comparison with other quinoproteins