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GIP (Glucose-dependent Insulinotropic Polypeptide) An incretin hormone that enhances insulin secretion and has effects on fat metabolism

and Geng, W

J Pharmacol Sci 2006

The primary advantages of GLP-1RAs lie in glucose reduction, cardiorenal benefits, and amelioration of metabolic syndrome, all of which are substantiated by a plethora of evidence-based studies [1,2,3,4]

When exposed to chronic alcohol-induced inflammation, HSCs become activated, transdifferentiating into myofibroblasts.10 These myofibroblasts are responsible for the excessive production of extracellular matrix (ECM) components, which leads to liver fibrosis, a key feature in the transition from early stage ALD to cirrhosis.10 The intricate and multifaceted pathogenesis of ALD also involves various other mediators that contribute to inflammation and fibrosis