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While EAE models have offered valuable insight into adaptive immune responses, demyelination, and axonal damage in MS, they fall short in replicating the full spectrum of human MS pathology, particularly the disease's onset and heterogeneity (Figure 5)

This led to CVS Health, Elevance Health, and Kaiser Permanente announcing their plans for medication coverage

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Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation

Ethanol Oxidative stress plays an important role in the pathogenesis of alcoholic liver damage