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These findings clearly show that GPX1 is irreplaceable by other selenoproteins in protecting against systemic oxidative stress, and GPX1 has a significant antioxidant function in the body ( FIGURE 1 On the surface, the mice after GPX1 KO performed normally, but these mice were susceptible to the production of oxidative substances, and when stimulated, they were easy to cause harm to mice and increase oxidative stress in vivo

In agreement with the Helsinki convention, healthy study subjects gave informed consent for blood donation

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Editorial: selenium, human health and chronic disease

For example, vitamin C is often included in glutathione supplements because it helps to regenerate oxidized glutathione and improve its stability