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Nevertheless, based on the data brought forward, it seems safe to conclude that the phenomenon of early worsening of pre-existing DRP was secondary to the initial and rapid improvement in glycemic control that occurred in SUSTAIN-6

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Within the CNS, intestinal GLP-1 exerts potent appetite suppression via effects exerted directly through GLP-1R activation within the hypothalamus

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Higher plasmatic SOD activity was also observed in MASLD subjects with high intrahepatic fat content (Monserrat-Mesquida et al

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