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[239] Polyphenols, encompassing flavonoids, phenolic acids, and polyphenolic amides renowned for their antioxidant traits, are found in food items like tea, berries, and dark chocolate

Even though NO is physiologically critical to vasodilation and neurotransmission (251), excess NO and RNS are damaging as they directly attack antioxidant enzymes such as catalase (298), promoting redox imbalance

Autophagy in the pathogenesis of disease

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[7] Mixed melasma exhibited both epidermal and dermal features, including pseudonetwork (55%), arcuate structures (60%), and increased globules (60%), alongside perifollicular sparing (65%) and enhanced vascularity, reflecting the microvascular influence supported by VEGF-driven pathways