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As you can imagine, a patient with this gain-of-function mutation will have elevated blood glucose, potentially leading to type II diabetes mellitus

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CrossRef Liquid-liquid phase separation of TRIM21 regulates EZH2-mediated ferroptosis to facilitate hepatocellular carcinoma progression Li Xu, Shilun Wu, Changyu Yao, Shaohong Wang Cytotechnology .2026;[Epub] CrossRef Genetically Engineered Membrane-Mimetic Liposome-Wrapped Violet Phosphorus Nanoplatform for Targeted Synergistic Ferroptosis/Photothermal/Immunotherapy of Hepatocellular Carcinoma Shuo Li, Zhixiong Wang, Meiling Zhou, Weilu Jia, Zonghan Shi, XinYu Mao, Weijie Zhao, Boyu Xia, Zhe Wang, Xinhao Li, YeWei Zhang ACS Applied Materials & Interfaces .2026

Cyclophosphamide, cisplatin, and carmustine: pharmacokinetics of carmustine following multiple alkylating-agent interactions