labial melanotic macule dermoscopy macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in dermoscopy: A pigmented labial lesion

2019 Jan 1;58(1):42-6

They cannot sense changes in the tissue microenvironment or adjust their activity, unlike stem cells, which adapt to the bodys needs

Bibcode:2014FrPS....5..442G

Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways

Patients received arGLP-1 based on availability and clinical appropriateness: semaglutide was administered via weekly subcutaneous injections, starting at 0.25 mg/week and titrated to a maximum dose of 1 mg/week, while dulaglutide was administered at a fixed dose of 1.5 mg/week