Overall, glutathiones neuroprotective efficacy in the CNS is intricately regulated by enzyme expression, metabolic substrate availability, and regional brain biochemistry, making it a pivotal target for intervention in oxidative stress-related neuropathologies
Less common but serious side effects include constipation, which can lead to skin issues such as bleeding and blistering, or burning feeling in the mouth
[6] This dose is gradually increased every 4 weeks, over 16 weeks of treatment
Juan Jin, [email protected] These authors have contributed equally to this work This article was submitted to Renal Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Neurology 103 , e209574 (2024)