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GLP-1 receptor agonists, including semaglutide, have been associated with acute pancreatitis in postmarketing surveillance, though a definitive causal relationship has not been established

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These are considered an alternative treatment to metformin, as their function lies in the modulation of the components that signal the insulin pathways, thus influencing processes such as the regulation of the menstrual cycle, carbohydrate metabolism, and hyperandrogenism