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The required dose is 20 to 40 mg/kg (i.e., 12 g in two divided doses) and significant effects are reported within a period of 3 months.[] ADVERSE EFFECTS ASSOCIATED WITH ORAL PREPARATIONS Local side effects can be expected like soreness of the gums caused by sucking the lozenges

This phenomenon, known as "reductive stress," occurs when the balance of oxidative and reductive environments in cells is disrupted

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