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Radiation-Induced Salivary Gland Dysfunction: Mechanisms, Therapeutics and Future Directions

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The safety and the convenience of use (once-daily or twice-daily doses in combination with metformin) of the DPP-4 inhibitors have made them one of the most commonly used drug options, particularly in the early stages of the disease, in patients with renal failure, and in elderly subjects.39 Glucagon-like peptide-1 (GLP-1) receptor agonists These drugs bind to the GLP-1 receptors, inducing a decrease in glucagon secretion and an increase in insulin secretion, both in a glycemia dependent manner

There are several reasons for this, including: Aging : It's estimated that glutathione levels decline by approximately 10% per decade after the age of 20