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Rarely, allergic reactions may occur

When Chapo was at the height of his power, following Mexicos bloody cartel wars of a decade ago, the country enjoyed a period of relative peace what the novelist and drug-war chronicler Don Winslow has dubbed the Pax Sinaloa. But much like how the Islamic State grew from the vacuum of post-Saddam Iraq, one unintended consequence of taking out Chapo may have been opening the door for someone even worse

Diarrhoea associated with linaclotide is usually dose-dependent and may be severe in some cases, occasionally leading to treatment discontinuation

Wang B, Li Y, Shao C, Tan Y, Cai L (2012) Cadmium and its epigenetic effects

This symptom is typically mild and is a known effect associated with GH elevation