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Paradoxine drives thermogenesis through TRPV1 receptor activation and brown adipose tissue (BAT) stimulation a separate heat-generating mechanism that operates through adrenergic and uncoupling protein pathways independent of carnitine

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Skin symptoms Autoimmune skin conditions like psoriasis, dermatomyositis, and lupus rashes may respond to the systemic anti-inflammatory effects of weight loss and reduced metabolic inflammation