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A recent study (87) has also shown that tetrandrine can improve RA by regulating neutrophil activity in AIA mice and reducing the formation of neutrophil extracellular traps induced by phorbol ester

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This dual agonist profile allows researchers to examine how simultaneous incretin receptor activation influences intracellular signaling pathways such as cyclic AMP signaling, receptor crosstalk, and endocrine pathway modulation in experimental systems