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[22,23] Extrafacial melasma revealed globular pigment (57%), focal hypopigmentation (57%), and prominent skin markings (71%), with reduced perifollicular sparing (43%) as illustrated in Figure 4, reflecting anatomic differences from facial melasma

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It should be noted that postmarketing reports of MTC have occurred with other GLP-1 receptor agonists (such as liraglutide), though causality has not been established