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Despite the role of mitochondria in neural energy production, few studies investigated the effect of thiamine supplementation on migraine
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For instance, metformin can achieve its glucose-lowering effects through the gut-liver axis ( Metformin can also exert its glucose-lowering effects through a gut-liver-brain axis ( 3 Adverse effects 3.1 Gastrointestinal effects Despite its widespread availability and affordability, metformin is associated with gastrointestinal side effects, including nausea, vomiting, diarrhea, and bloating, affecting around 20% of patients ( E
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