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Within the nutraceuticals market, it holds a share of around 1-2% , as broader categories like vitamins and minerals dominate

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During active disease, higher levels of Eggerthella (a genus associated with intestinal inflammation) have been found, which might loosen the gut barrier and allow more immune activation [184]

TGF-1 expression is increased in ligated UOO mouse kidneys 56 or kidneys of patients with diabetic nephropathy 57 and circulating TGF-1 is elevated in conditions that are risk factors for CKD including hypertension, dyslipidemia and T2D 58

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