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Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to pulmonary artery constriction

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Finally, we provide proof of principle that systemic administration of a glucagon-like peptide 1coupled (GLP1-coupled), Sirt2-targeting antisense oligonucleotide achieves cell Sirt2 inactivation and stimulates cell proliferation during hyperglycemia