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Studies have shown that LGG colonization of the intestine can promote the growth of microbiota, epithelial cell proliferation, differentiation, tight junction formation, IgA production and maturation during development, and reduce the risk of intestinal injury and colitis in adult mice (Donato et al., 2010)

In the present study, we found that GSTP prevented nuclear-cytoplasmic translocation of HMGB1, which strongly suggested that GSTP functioned in nucleus of the macrophage

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