Bizino MB, Jazet IM, de Heer P et al (2020) Placebo-controlled randomised trial with liraglutide on magnetic resonance endpoints in individuals with type 2 diabetes: a pre-specified secondary study on ectopic fat accumulation
Recommendation: Take 1 capsule twice daily, one hour away from food or drink other than water, or as recommended by your healthcare professional
First, GLP-1 receptor agonists carry an FDA black box warning about thyroid C-cell tumors based on animal studies, and while the clinical relevance in humans remains uncertain, the warning does mean patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 should not take these medications
Seek emergency help immediately if chest pain is accompanied by any of the following: sudden collapse or fainting, severe shortness of breath, pain radiating to the jaw, neck, shoulder, or arm (particularly the left arm), profuse sweating, nausea or vomiting with lightheadedness, or the sudden inability to speak or move
It works by activating two key hormones, GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), that help regulate blood sugar, suppress appetite, and support improved metabolic function