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The small molecule inhibitors or gene silencing of GLS1 expression has shown antitumor activity in a variety of cancers, including melanoma (Varghese et al., 2021), breast cancer (Gross et al., 2014), pancreatic cancer (Son et al., 2013), acute myeloid leukemia (Emadi et al., 2014), and malignant glioma (Yamashita et al., 2021)

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Ca 2+ influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes

Please note: potential side effects of glutathione-based treatments include abdominal cramps and certain allergic reactions (e.g

Alpha-Lipoic Acid Alpha-lipoic acid is a multifunctional compound in its ability to serve as a direct scavenger of free radical species and to also help in the regeneration of endogenous antioxidants such as glutathione