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In addition, the Western blot analysis further showed that the HFD-induced suppression of IR, IRS-1, p-AMPK, and p-ACC expression in the liver was also altered by NaB (Fig

In contrast, PWA mice display overt metabolic perturbations, including overweight and impaired glucose homeostasis 46 , and may mimic the canonical human phenotype A of PCOS linked to hyperandrogenism, anovulatory cycles, and polycystic ovarian morphology 45

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