Most of the studies evaluated the cardiovascular outcomes using a composite outcome of major adverse cardiac events (MACE) or one of its components, cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke
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In contrast, Nrf2 activators, such as sulforaphane, have been found to prevent homocysteine- or hydrogen peroxide-induced cataract formation in human lens epithelial cells by increasing nuclear translocation of Nrf2 and expressions of cellular antioxidants, including catalase, superoxide dismutase, glutathione peroxidase, and glutathione