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Mild to moderate transient gastrointestinal side effects were the most frequently reported adverse events associated with tirzepatide treatment (nausea 12%18% vs

In conclusion, PCs can alleviate diabetes-induced myocardial hypertrophy, cardiac fibrosis, and heart failure, demonstrating potential cardioprotective effects by regulating the S100A11/RAGE/PPAR signaling pathway, improving mitochondrial function, reducing oxidative stress, and inhibiting the formation of AGEs

10.1210/endo-127-5-2217 45 LeiS.ClydesdaleL.DaiA.CaiX.FengY.YangD.et al (2018)

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