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In the central nervous system, niacin is known as a key mediator of neuronal development and survival (37)

Oxid Med Cell Longev 2020:3818196

In melanoma, downregulation of IGF-1 reduces the dry character of melanoma initiating cells, including the expression of dry markers (SOX2, Oct-3/4, CD24 and CD133) and functional properties (melanosphere formation, aldehyde dehydrogenase activity and side population) and eventually inhibiting the proliferation and metastasis of tumor cells (26)

This may not be necessary every time you have injections, but regular testing is helpful to track your progress

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