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doi: 10.1186/1475-2875-9-118 2 AmiriM.NourianA.KhoshkamM.RamazaniA

The decreased reproductive performance of SLC7A11 knockout male mice was supported by a high proportion of immature spermatozoa in the cauda epididymis, although there were no significant differences in cysteine and GSH levels in the testis compared to controls, suggesting GSH synthesized by xCT is considered to be an important antioxidant [76]

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Figure 2 To mitigate the damage caused by ferroptosis in various neuronal cells, the responses of the iron detoxification and antioxidant systems may function as important endogenous protective mechanisms in VaD

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