N Engl J Med 381(9): 841 851 Fudim M, White J, Pagidipati NJ, Lokhnygina Y, Wainstein J, Murin J, Iqbal N, hman P, Lopes RD, Reicher B, Holman RR, Hernandez AF, Mentz RJ (2019) Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes Mellitus With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial
Symptoms of dyspepsia, nausea, vomiting, bloating, diarrhea, and constipation stand out among the gastrointestinal adverse effects described.514 The presence of gastrointestinal adverse effects associated with antidiabetics has an overall impact on the patient with diabetes, given that they can increase the need for medical attention, affect quality of life due to the symptoms they trigger, and modify therapeutic regimens
Allergic Reactions: When an immune system encounters an allergen, a non harmful substance that the immune system considers a threat and it sends large quantities of histamine
In each test, mice were tested individually and the equipment cleaned between each animal (except when tests utilised home cages)
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