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Notably, DRP-104 demonstrates the ability to counter T cell exhaustion and enhance the functionality of both CD4 + and CD8 + T cells [188]

This dysbiosis features: Enrichment of opportunistic pathogens ( Collinsella aerofaciens , Streptococcus infantis ) Depletion of beneficial bacteria, especially short-chain fatty acid producers Notably, these alterations persist long after infection resolution, with dysbiosis documented up to 6 months post-recovery

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Glutamate-modulating drugs are, therefore, becoming more and more popular for treating OCD and OCRD

Future research should explore the longerterm effects of GLP1 RAs and include more diverse populations to confirm and enhance the generalizability of our findings