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4 Prospect In-depth study of GPX family members has helped to discover not only the function of individual GPXs, but also the function of hydroperoxides as mediators in redox regulation

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Moreover, VK2 suppresses the MAPK/NF-B axis, resulting in decreased production of MMP3 and MMP13, while enhancing the synthesis of type II collagen and proteoglycans, so collectively mitigating ECM breakdown [114]