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Medical weight loss should be supervised, personalized, and focused on long-term metabolic health, not just the number on the scale

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It is worth mentioning that we also used univariable MR (UVMR) and multivariable MR (MVMR) analyses to identify the risk factors whose effects on MASLD were independent of BMI to figure out whether the causal effect of GLP-1R-based agonists on MASLD was fully dependent on their weight-loss effect

Acetyl Hexapeptide-8 (Argireline) is a 6-amino-acid peptide that mimics the N-terminus of SNAP-25 and inhibits the release of acetylcholine at the neuromuscular junction in muscle adjacent to dermis

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