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Mitochondrial diseases are characterized by both a diminished capacity to produce ATP as well as an elevated production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) [3]

Why Treatment is Crucial The standard of care for SPCD is lifelong supplementation with L-carnitine [6] [3]

It primarily works by reducing the amount of glucose (sugar) your liver produces and releases into your bloodstream

The proteomics data from this study are available at Pride database under the accession code (PXD046439)

Western blot assay K7M2 cells were incubated with the PBS, Ru(II)-OH, NP2, or NP4 (10 M Ru) for 12 h at 37 C, and the supernatant was subsequently co-incubated with RAW264.7 cells