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A single-masked study involving 120 HF patients reported significant improvements in NYHA class, BNP, LVEF, and metabolic biomarkers after SMI administration, with superior effects compared to trimetazidine, suggesting a synergistic advantage of multitarget interventions (Wang et al., 2020b)

The side effects are very less as compared to the benefits of the injections

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[DOI] [PubMed] [Google Scholar] 10.Mignogna MD, Lo Muzio L, Ruoppo E, Errico M, Amato M, Satriano RA

Neither showed significant effects on total cholesterol, HDL, or LDL