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After 1 year, the patient's BMI was maintained at 48.5 kg/m 2 , and she was satisfied on a diet of 1,000 kcal/day diet comprised of carbohydrates (100 g), proteins (48 g), and fat (42 g)

People with diabetes, particularly severe diabetes, tend to lose less weight with GLP-1s than people without diabetes, so microdosing is less likely to be as effective, though their dose should only be increased as they tolerate it. George said that in her professional opinion, microdosing is a potential option for patients with smaller amounts of weight to lose or as a bridge to start, or wean off, regular GLP-1 medications