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Certain conditions may contraindicate semaglutide usage, including a history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2

Therapeutic experience in patients 75 years of age is limited and a higher risk of general adverse reactions cannot be excluded." Similar statements appear in the Saxenda and Zepbound SmPCs

Pack them in your carry-on Checked luggage can swing to temperature extremes in the cargo hold

Beyond that, benefits plateau while risks (like too much caffeine) increase