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1 Introduction Lipid peroxidation is a complex process in which oxidants attack lipids-containing carbon-carbon double bonds, leading to oxidative degradation of lipids, formation of lipid peroxides, and subsequent cellular condition change ( + T cells in PD-L1 blockade therapy induced increased lipid peroxidation in tumor cells and contributed to the antitumor efficacy of immunotherapy ( 2 An overview of lipid peroxidation Lipid peroxidation is a metabolic process that involves the oxidative degradation of lipids and consists of three stages: initiation, propagation, and termination ( Figure 1 )

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doi: 10.1016/j.cell.2019.01.016 83 GallEP

I., Yoshino, J., Kelly, S

Used pens can be refrigerated at 36F to 46F (2C to 8C) or stored at room temperature between 59F and 86F (15C to 30C) for up to 56 days after the first use