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A 2009 study gave breast cancer patients 75mg daily for 28 days and found that there were no effects on radiation-induced fatigue or depression.79 And an older study that gave 45 elderly volunteers 1g of guarana found no significant sleep quality, cognitive, or sexual improvements.80 Natural caffeine (from Green Tea) 50mg While there isnt much research on caffeine for female sexual health, the results of a 2023 study showed that, compared to a placebo, acute administration of 300mg of caffeine (around six times the amount in this supplement) increased genital arousal in women experiencing sexual dysfunction due to antidepressants.81 Saffron extract 30mg There are a few positive studies that suggest saffron supplementation may be beneficial for sexual dysfunction
These changes suggested L-Cn triggers multiple metabolic reprogramming and functional reinventing on immune cells
doi: 10.1016/0378-4274(95)03532-x
Leonard MM, Valitutti F, Karathia H et al (2021) Microbiome signatures of progression toward celiac disease onset in at-risk children in a longitudinal prospective cohort study
While there is less research on these 2 supplements, initial trials over the last decade has been mixed with some promising data beginning to emerge
