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The reliance on natural sunlight and specific temperature requirements restricts commercial Spirulina production in open ponds to tropical and subtropical regions, limiting wider global production and potentially increasing transportation costs

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In addition, -HB exerts neuroprotective effects by attenuating microglial activation through stimulation of the hydroxycarboxylic acid receptor 2 (HCA2)

The cells were then incubated with the DCFH probe in a working solution for 30 min and subsequently washed with HBSS