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The way we know its the gut bacteria thats doing it, is that if you give people antibiotics to wipe out gut bacteria, you can apparently eat all the steak you want without making any TMAO

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Chem Rev 108 , 16871707, (2008)

The effects of acetyl-l-carnitine on the expression of these neurotrophins in pain conditions is still debated, but an anti-hyperalgesic effect could derive from a better harmonisation of their activity

Patients should consult their prescribing provider about alcohol consumption during treatment